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Giant Osteoclast Formation and Long-Term Oral Bisphosphonate Therapy

BACKGROUND: Bisphosphonates decrease bone resorption and are commonly used to treat or prevent osteoporosis. However, the effect of bisphosphonates on their target cells remains enigmatic, since in patients benefiting from therapy, little change, if any, has been observed in the number of osteoclast...

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Detalhes bibliográficos
Main Authors: Weinstein, Robert S., Roberson, Paula K., Manolagas, Stavros C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866022/
https://ncbi.nlm.nih.gov/pubmed/19118304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0802633
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