Nucleotide substitution at major histocompatibility complex class II loci: evidence for overdominant selection.
To study the mechanism of maintenance of polymorphism at major histocompatibility complex (MHC) loci, synonymous and nonsynonymous (amino acid-altering) nucleotide substitutions in the putative antigen-recognition site (included in the first domain of the MHC molecule) and other regions of human and...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1989
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2492668/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.3.958 |
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