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Nucleotide substitution at major histocompatibility complex class II loci: evidence for overdominant selection.

To study the mechanism of maintenance of polymorphism at major histocompatibility complex (MHC) loci, synonymous and nonsynonymous (amino acid-altering) nucleotide substitutions in the putative antigen-recognition site (included in the first domain of the MHC molecule) and other regions of human and...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Hughes, A L, Nei, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1989
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286598/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2492668/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.3.958
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