Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups

Warfarin-dosing algorithms incorporating CYP2C9 and VKORC1 −1639G>A improve dose prediction compared with algorithms based solely on clinical and demographic factors. However, these algorithms better capture dose variability among whites than Asians or blacks. Herein, we evaluate whether other VK...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Limdi, Nita A., Wadelius, Mia, Cavallari, Larisa, Eriksson, Niclas, Crawford, Dana C., Lee, Ming-Ta M., Chen, Chien-Hsiun, Motsinger-Reif, Alison, Sagreiya, Hersh, Liu, Nianjun, Wu, Alan H. B., Gage, Brian F., Jorgensen, Andrea, Pirmohamed, Munir, Shin, Jae-Gook, Suarez-Kurtz, Guilherme, Kimmel, Stephen E., Johnson, Julie A., Klein, Teri E., Wagner, Michael J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2010
Pynciau:
Thrombosis and Hemostasis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865873/
https://ncbi.nlm.nih.gov/pubmed/20203262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-255992
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