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Human tissue transglutaminase is inhibited by pharmacologic and chemical acetylation
Human tissue transglutaminase (TGM2) is implicated in the pathogenesis of several neurodegenerative disorders including Alzheimer's, Parkinson's and expanded polyglutamine (polyQ) diseases. TGM2 promotes formation of soluble and insoluble high molecular weight aggregates by catalyzing a co...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865712/ https://ncbi.nlm.nih.gov/pubmed/19998405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.301 |
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