Akt1 controls macrophage response to LPS by regulating microRNAs

MicroRNAs regulated by LPS target genes that contribute to the inflammatory phenotype. Here we show that Akt1, which is activated by LPS, differentially regulates miRNAs including let-7e, miR-155, miR-181c and miR125b. In silico analyses and transfection studies revealed that let-7e represses TLR4 w...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Androulidaki, Ariadne, Iliopoulos, Dimitrios, Arranz, Alicia, Doxaki, Christina, Schworer, Steffen, Zacharioudaki, Vassiliki, Margioris, Andrew N., Tsichlis, Philip N., Tsatsanis, Christos
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2009
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865583/
https://ncbi.nlm.nih.gov/pubmed/19699171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.06.024
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