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Corticotrophin-Releasing Factor (CRF) and the Urocortins Are Potent Regulators of the Inflammatory Phenotype of Human and Mouse White Adipocytes and the Differentiation of Mouse 3T3L1 Pre-Adipocytes

Chronic activation of innate immunity takes place in obesity and initiated by the hypertrophic adipocytes which obtain a pro-inflammatory phenotype. The corticotrophin-releasing factor (CRF) family of neuropeptides and their receptors (CRF(1) and CRF(2)) affect stress response and innate immunity. A...

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Bibliographic Details
Main Authors: Dermitzaki, Eirini, Liapakis, George, Androulidaki, Ariadne, Venihaki, Maria, Melissas, John, Tsatsanis, Christos, Margioris, Andrew N.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024041/
https://ncbi.nlm.nih.gov/pubmed/24835211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097060
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