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Knowledge-guided gene ranking by coordinative component analysis

BACKGROUND: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those genes that are strongly associated with the functionality of a network. Traditional statistical methods are often inept to id...

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Detalhes bibliográficos
Main Authors: Wang, Chen, Xuan, Jianhua, Li, Huai, Wang, Yue, Zhan, Ming, Hoffman, Eric P, Clarke, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865494/
https://ncbi.nlm.nih.gov/pubmed/20353603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-162
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