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Knowledge-guided multi-scale independent component analysis for biomarker identification

BACKGROUND: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical methods often fail to identify biologically meaningful biomarkers related to a specific disease under study. In this pap...

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Detalhes bibliográficos
Main Authors: Chen, Li, Xuan, Jianhua, Wang, Chen, Shih, Ie-Ming, Wang, Yue, Zhang, Zhen, Hoffman, Eric, Clarke, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576264/
https://ncbi.nlm.nih.gov/pubmed/18837990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-416
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