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N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor

BACKGROUND: Microglia provide continuous immune surveillance of the CNS and upon activation rapidly change phenotype to express receptors that respond to chemoattractants during CNS damage or infection. These activated microglia undergo directed migration towards affected tissue. Importantly, the mo...

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書誌詳細
主要な著者: McHugh, Douglas, Hu, Sherry SJ, Rimmerman, Neta, Juknat, Ana, Vogel, Zvi, Walker, J Michael, Bradshaw, Heather B
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865488/
https://ncbi.nlm.nih.gov/pubmed/20346144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-44
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