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siRNA knockdown of GPR18 receptors in BV-2 microglia attenuates N-arachidonoyl glycine-induced cell migration

BACKGROUND: Neurons are known to employ the endogenous cannabinoid system to communicate with other cells of the CNS. Endocannabioid signaling recruits microglia toward neurons by engaging cannabinoid CB(2) and abnormal cannabidiol (Abn-CBD) receptors. The Abn-CBD receptor is a prominent atypical ca...

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Detalhes bibliográficos
Main Authors: McHugh, Douglas, Wager-Miller, James, Page, Jeremy, Bradshaw, Heather B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493281/
https://ncbi.nlm.nih.gov/pubmed/22834922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-7-10
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