N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor

BACKGROUND: Microglia provide continuous immune surveillance of the CNS and upon activation rapidly change phenotype to express receptors that respond to chemoattractants during CNS damage or infection. These activated microglia undergo directed migration towards affected tissue. Importantly, the mo...

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Główni autorzy: McHugh, Douglas, Hu, Sherry SJ, Rimmerman, Neta, Juknat, Ana, Vogel, Zvi, Walker, J Michael, Bradshaw, Heather B
Format: Artigo
Język:Inglês
Wydane: BioMed Central 2010
Hasła przedmiotowe:
Research article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865488/
https://ncbi.nlm.nih.gov/pubmed/20346144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-44
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