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The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

The lungs are generated by branching morphogenesis as a result of reciprocal signalling interactions between the epithelium and mesenchyme during development. Mutations that disrupt formation of either the correct number or shape of epithelial branches affect lung function. This, in turn, can lead t...

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書誌詳細
主要な著者: Yates, Laura L., Schnatwinkel, Carsten, Murdoch, Jennifer N., Bogani, Debora, Formstone, Caroline J., Townsend, Stuart, Greenfield, Andy, Niswander, Lee A., Dean, Charlotte H.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865378/
https://ncbi.nlm.nih.gov/pubmed/20223754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq104
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