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The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

The lungs are generated by branching morphogenesis as a result of reciprocal signalling interactions between the epithelium and mesenchyme during development. Mutations that disrupt formation of either the correct number or shape of epithelial branches affect lung function. This, in turn, can lead t...

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Bibliografiske detaljer
Main Authors: Yates, Laura L., Schnatwinkel, Carsten, Murdoch, Jennifer N., Bogani, Debora, Formstone, Caroline J., Townsend, Stuart, Greenfield, Andy, Niswander, Lee A., Dean, Charlotte H.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865378/
https://ncbi.nlm.nih.gov/pubmed/20223754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq104
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