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Angiotensin II Stimulates Thick Ascending Limb NO Production via AT(2) Receptors and Akt1-dependent Nitric-oxide Synthase 3 (NOS3) Activation

Angiotensin II (Ang II) acutely stimulates thick ascending limb (TAL) NO via an unknown mechanism. In endothelial cells, activation of Ang II type 2 receptor (AT(2)) stimulates NO. Akt1 activates NOS3 by direct phosphorylation. We hypothesized that Ang II stimulates TAL NO production via AT(2)-media...

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Bibliografski detalji
Glavni autori: Herrera, Marcela, Garvin, Jeffrey L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865342/
https://ncbi.nlm.nih.gov/pubmed/20299462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.109041
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