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Angiotensin II Stimulates Thick Ascending Limb NO Production via AT(2) Receptors and Akt1-dependent Nitric-oxide Synthase 3 (NOS3) Activation
Angiotensin II (Ang II) acutely stimulates thick ascending limb (TAL) NO via an unknown mechanism. In endothelial cells, activation of Ang II type 2 receptor (AT(2)) stimulates NO. Akt1 activates NOS3 by direct phosphorylation. We hypothesized that Ang II stimulates TAL NO production via AT(2)-media...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865342/ https://ncbi.nlm.nih.gov/pubmed/20299462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.109041 |
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