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Topologically Random Insertion of EmrE Supports a Pathway for Evolution of Inverted Repeats in Ion-coupled Transporters

Inverted repeats in ion-coupled transporters have evolved independently in many unrelated families. It has been suggested that this inverted symmetry is an essential element of the mechanism that allows for the conformational transitions in transporters. We show here that small multidrug transporter...

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Detalhes bibliográficos
Main Authors: Nasie, Iris, Steiner-Mordoch, Sonia, Gold, Ayala, Schuldiner, Shimon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865334/
https://ncbi.nlm.nih.gov/pubmed/20308069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.108746
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