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Crosslinking of membrane-embedded cysteines reveals contact points in the EmrE oligomer

EmrE is a small multidrug transporter that extrudes various drugs in exchange with protons, thereby rendering Escherichia coli cells resistant to these compounds. In this study, relative helix packing in the EmrE oligomer solubilized in detergent was probed by intermonomer crosslinking analysis. Uni...

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Bibliografske podrobnosti
Main Authors: Soskine, Misha, Steiner-Mordoch, Sonia, Schuldiner, Shimon
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC129395/
https://ncbi.nlm.nih.gov/pubmed/12221291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192392899
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