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Crosslinking of membrane-embedded cysteines reveals contact points in the EmrE oligomer

EmrE is a small multidrug transporter that extrudes various drugs in exchange with protons, thereby rendering Escherichia coli cells resistant to these compounds. In this study, relative helix packing in the EmrE oligomer solubilized in detergent was probed by intermonomer crosslinking analysis. Uni...

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Hlavní autoři: Soskine, Misha, Steiner-Mordoch, Sonia, Schuldiner, Shimon
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC129395/
https://ncbi.nlm.nih.gov/pubmed/12221291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192392899
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