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Undecided membrane proteins insert in random topologies Up, down and sideways: it doesn’t really matter

It is usually assumed that to ensure proper function, membrane proteins must be inserted in a unique topology. However, a number of dimeric small multidrug transporters can function in the membrane in various topologies. Thus, the dimers can be a random mixture of N(i)C(i) (N- and C-termini facing t...

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Bibliografski detalji
Glavni autor: Schuldiner, Shimon
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372635/
https://ncbi.nlm.nih.gov/pubmed/22444835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2012.02.006
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