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Undecided membrane proteins insert in random topologies Up, down and sideways: it doesn’t really matter
It is usually assumed that to ensure proper function, membrane proteins must be inserted in a unique topology. However, a number of dimeric small multidrug transporters can function in the membrane in various topologies. Thus, the dimers can be a random mixture of N(i)C(i) (N- and C-termini facing t...
Αποθηκεύτηκε σε:
| Κύριος συγγραφέας: | |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372635/ https://ncbi.nlm.nih.gov/pubmed/22444835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2012.02.006 |
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