Bis(benzyl)polyamine analogs inhibit the growth of chloroquine-resistant human malaria parasites (Plasmodium falciparum) in vitro and in combination with alpha-difluoromethylornithine cure murine malaria.

A number of bis(benzyl)polyamine analogs were found to be potent inhibitors of both chloroquine-resistant and chloroquine-sensitive strains of the human malaria parasite Plasmodium falciparum in vitro (IC50 values = 0.2-14 microM). Administration of one of the compounds, MDL 27695, which is N,N'...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Bitonti, A J, Dumont, J A, Bush, T L, Edwards, M L, Stemerick, D M, McCann, P P, Sjoerdsma, A
格式: Artigo
語言:Inglês
出版: 1989
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC286531/
https://ncbi.nlm.nih.gov/pubmed/2463635
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍