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bis(benzyl)polyamine analogues are substrates for a mammalian cell-transport system which is distinct from the polyamine-transport system.

Bis(benzyl)polyamine analogues (e.g. NN'-bis(3-[(phenylmethyl)amino]propyl)-1,8-diamino-octane [C6H5CH2NH-(CH2)3NH(CH2)8NH(CH2)3NHCH2C6H5]) have previously been shown to regulate polyamine biosynthesis and growth of rat hepatoma (HTC) cells. Saturable uptake of the analogues, the ability of oth...

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Autori principali: Byers, T L, Bitonti, A J, McCann, P P
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131527/
https://ncbi.nlm.nih.gov/pubmed/2115774
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