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Engineered Interfaces of an AAA(+) ATPase Reveal a New Nucleotide-dependent Coordination Mechanism

Homohexameric ring AAA(+) ATPases are found in all kingdoms of life and are involved in all cellular processes. To accommodate the large spectrum of substrates, the conserved AAA(+) core has become specialized through the insertion of specific substrate-binding motifs. Given their critical roles in...

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Detalles Bibliográficos
Main Authors: Joly, Nicolas, Buck, Martin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865273/
https://ncbi.nlm.nih.gov/pubmed/20197281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.103150
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