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Activation of Peripheral κ Opioid Receptors Inhibits Capsaicin-Induced Thermal Nociception in Rhesus Monkeys

8-Methyl-N-vanillyl-6-nonenamide (capsaicin) was locally applied in the tail of rhesus monkeys to evoke a nociceptive response, thermal allodynia, which was manifested as reduced tail-withdrawal latencies in normally innocuous 46°C water. Coadministration of three κ opioid ligands, U50,488 (3.2–100...

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Detaylı Bibliyografya
Asıl Yazarlar: Ko, Mei-Chuan, Butelman, Eduardo R., Woods, James H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865196/
https://ncbi.nlm.nih.gov/pubmed/10087027
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