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Allelic Imbalance at p53 and Microsatellite Instability Are Predictive Markers for Resistance to Chemotherapy in Gastric Carcinoma

BACKGROUND: Combined treatment with 5-fluorouracil and cisplatin (FP chemotherapy) is an effective neoadjuvant regimen for gastric carcinoma. However, it is ineffective in half of all patients. This study tests the hypothesis that genetic markers might identify those patients with gastric cancer who...

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Hlavní autoři: Yashiro, Masakazu, Inoue, Toru, Nishioka, Nobuaki, Matsuoka, Tasuku, Boland, C. Richard, Hirakawa, Kosei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865194/
https://ncbi.nlm.nih.gov/pubmed/19597886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-009-0590-6
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