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Allelic Imbalance at p53 and Microsatellite Instability Are Predictive Markers for Resistance to Chemotherapy in Gastric Carcinoma

BACKGROUND: Combined treatment with 5-fluorouracil and cisplatin (FP chemotherapy) is an effective neoadjuvant regimen for gastric carcinoma. However, it is ineffective in half of all patients. This study tests the hypothesis that genetic markers might identify those patients with gastric cancer who...

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Detalhes bibliográficos
Principais autores: Yashiro, Masakazu, Inoue, Toru, Nishioka, Nobuaki, Matsuoka, Tasuku, Boland, C. Richard, Hirakawa, Kosei
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865194/
https://ncbi.nlm.nih.gov/pubmed/19597886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-009-0590-6
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