Short Interfering RNA against Transient Receptor Potential Vanilloid 1 Attenuates Cisplatin-Induced Hearing Loss in the Rat

Cisplatin, a chemotherapeutic agent of choice for the treatment of solid tumors, produces hearing loss in approximately half a million new cancer patients annually in the United States. The hearing loss is due, in part, to increased generation of reactive oxygen species (ROS) in the cochlea, leading...

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Hlavní autoři: Mukherjea, Debashree, Jajoo, Sarvesh, Whitworth, Craig, Bunch, Jennifer R., Turner, Jeremy G., Rybak, Leonard P., Ramkumar, Vickram
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865180/
https://ncbi.nlm.nih.gov/pubmed/19052196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1307-08.2008
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