ACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteria

Mycolic acids are essential for the survival, virulence and antibiotic resistance of the human pathogen Mycobacterium tuberculosis. Inhibitors of mycolic acid biosynthesis, such as isoniazid and ethionamide, have been used as efficient drugs for the treatment of tuberculosis. However, the increase i...

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Detaylı Bibliyografya
Asıl Yazarlar: Kurth, Daniel G., Gago, Gabriela M., de la Iglesia, Agustina, Bazet Lyonnet, Bernardo, Lin, Ting-Wan, Morbidoni, Héctor R., Tsai, Shiou-Chuan, Gramajo, Hugo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Microbiology Society 2009
Konular:
Physiology and Biochemistry
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865140/
https://ncbi.nlm.nih.gov/pubmed/19423629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.027714-0
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