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Analysis of the sequence-specific interactions between Cro repressor and operator DNA by systematic base substitution experiments.

We measured quantitatively the binding affinities of purified Cro repressor to the chemically synthesized wild-type and mutant OR1 operators, consisting of all three possible base-pair substitutions and of thymine to uracil substitutions at each base-pair position of the 17-base-pair operator sequen...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Takeda, Y, Sarai, A, Rivera, V M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286485/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2911590/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.2.439
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