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p53-Induced Growth Arrest Is Regulated by the Mitochondrial SirT3 Deacetylase
A hallmark of p53 function is to regulate a transcriptional program in response to extracellular and intracellular stress that directs cell cycle arrest, apoptosis, and cellular senescence. Independent of the role of p53 in the nucleus, some of the anti-proliferative functions of p53 reside within t...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864751/ https://ncbi.nlm.nih.gov/pubmed/20463968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010486 |
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