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Crystallization and preliminary X-ray crystallographic analysis of the tetracycline-degrading monooxygenase TetX2 from Bacteroides thetaiotaomicron

The flavin-dependent monooxygenase TetX2 from Bacteroides thetaiotaomicron confers resistance against tetracyclines in aerobically grown Escherichia coli. TetX2 modifies several tetracycline antibiotics by regioselective hydroxylation of the substrates to 11a-hydroxy-tetracyclines. X-ray diffraction...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Volkers, Gesa, Schuldt, Linda, Palm, Gottfried J., Wright, Gerard D., Hinrichs, Winfried
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864705/
https://ncbi.nlm.nih.gov/pubmed/20445272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430911001225X
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