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Cytotoxic Ribonucleases: The Dichotomy of Coulombic Forces

Cells tightly regulate their contents. Still, nonspecific Coulombic interactions between cationic molecules and anionic membrane components can lead to adventitious endocytosis. Here, we characterize this process in a natural system. To do so, we create variants of human pancreatic ribonuclease (RNa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Johnson, R. Jeremy, Chao, Tzu-Yuan, Lavis, Luke D., Raines, Ronald T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864629/
https://ncbi.nlm.nih.gov/pubmed/17705507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700857u
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