Marked in vivo antiretrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine, a selective anti-human immunodeficiency virus agent.

9-(2-Phosphonylmethoxyethyl)adenine (PMEA) is a potent and selective inhibitor of the replication of human immunodeficiency virus (HIV) in vitro in human T-lymphocyte MT-4, H9, and ATH8 cells. PMEA also inhibits Moloney murine sarcoma virus (Mo-MSV)-induced transformation of murine C3H embryo fibrob...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Balzarini, J, Naesens, L, Herdewijn, P, Rosenberg, I, Holy, A, Pauwels, R, Baba, M, Johns, D G, De Clercq, E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286458/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2911579/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.1.332
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