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9-(2-Phosphonylmethoxyethyl)adenine in the treatment of murine acquired immunodeficiency disease and opportunistic herpes simplex virus infections.

The murine model of acquired immunodeficiency disease was used to evaluate both the antiretroviral and antiherpetic activities of the acyclic nucleotide analog 9-(2-phosphonylmethoxyethyl)adenine (PMEA). The antiretroviral activity of PMEA was compared with that of azidothymidine (AZT) in mice recei...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Gangemi, J D, Cozens, R M, De Clercq, E, Balzarini, J, Hochkeppel, H K
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1989
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172778/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2482011/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.11.1864
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