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9-(2-Phosphonylmethoxyethyl)adenine in the treatment of murine acquired immunodeficiency disease and opportunistic herpes simplex virus infections.

The murine model of acquired immunodeficiency disease was used to evaluate both the antiretroviral and antiherpetic activities of the acyclic nucleotide analog 9-(2-phosphonylmethoxyethyl)adenine (PMEA). The antiretroviral activity of PMEA was compared with that of azidothymidine (AZT) in mice recei...

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Detalles Bibliográficos
Main Authors: Gangemi, J D, Cozens, R M, De Clercq, E, Balzarini, J, Hochkeppel, H K
Formato: Artigo
Idioma:Inglês
Publicado: 1989
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC172778/
https://ncbi.nlm.nih.gov/pubmed/2482011
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