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9-(2-Phosphonylmethoxyethyl)adenine in the treatment of murine acquired immunodeficiency disease and opportunistic herpes simplex virus infections.

The murine model of acquired immunodeficiency disease was used to evaluate both the antiretroviral and antiherpetic activities of the acyclic nucleotide analog 9-(2-phosphonylmethoxyethyl)adenine (PMEA). The antiretroviral activity of PMEA was compared with that of azidothymidine (AZT) in mice recei...

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Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Gangemi, J D, Cozens, R M, De Clercq, E, Balzarini, J, Hochkeppel, H K
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1989
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172778/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2482011/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.11.1864
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