Basal core promoters control the equilibrium between negative cofactor 2 and preinitiation complexes in human cells

BACKGROUND: The general transcription factor TFIIB and its antagonist negative cofactor 2 (NC2) are hallmarks of RNA polymerase II (RNAPII) transcription. Both factors bind TATA box-binding protein (TBP) at promoters in a mutually exclusive manner. Dissociation of NC2 is thought to be followed by TF...

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Detalhes bibliográficos
Main Authors: Albert, Thomas K, Grote, Korbinian, Boeing, Stefan, Meisterernst, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864573/
https://ncbi.nlm.nih.gov/pubmed/20230619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-3-r33
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