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Ca(2+) Induces the Formation of Two Distinct Subpopulations of Single Group II Intron Molecules

[Image: see text] The folding pathway of the Sc.ai5γ derived group II intron ribozyme D135 is highly specific to the correct M(2+) cofactor. Upon partial replacement of Mg(2+) with Ca(2+), the molecules split into two distinct static subpopulations that are not interchangeable. Type 2 molecules ther...

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Autors principals: Steiner, Miriam, Rueda, David, Sigel, Roland K. O.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864518/
https://ncbi.nlm.nih.gov/pubmed/19924747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200903809
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