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Ca(2+) Induces the Formation of Two Distinct Subpopulations of Single Group II Intron Molecules
[Image: see text] The folding pathway of the Sc.ai5γ derived group II intron ribozyme D135 is highly specific to the correct M(2+) cofactor. Upon partial replacement of Mg(2+) with Ca(2+), the molecules split into two distinct static subpopulations that are not interchangeable. Type 2 molecules ther...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864518/ https://ncbi.nlm.nih.gov/pubmed/19924747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200903809 |
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