Mitochondrial DNA copy number and lung cancer risk in a prospective cohort study

Mitochondria are eukaryotic organelles responsible for energy production. Mitochondrial DNA (mtDNA) lack introns and protective histones, have limited DNA repair capacity and compensate for damage by increasing the number of mtDNA copies. As a consequence, mitochondria are more susceptible to reacti...

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Main Authors: Hosgood, H.Dean, Liu, Chin-San, Rothman, Nathaniel, Weinstein, Stephanie J., Bonner, Matthew R., Shen, Min, Lim, Unhee, Virtamo, Jarmo, Cheng, Wen-ling, Albanes, Demetrius, Lan, Qing
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Molecular Epidemiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864414/
https://ncbi.nlm.nih.gov/pubmed/20176654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq045
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