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Mitochondrial DNA copy number and lung cancer risk in a prospective cohort study
Mitochondria are eukaryotic organelles responsible for energy production. Mitochondrial DNA (mtDNA) lack introns and protective histones, have limited DNA repair capacity and compensate for damage by increasing the number of mtDNA copies. As a consequence, mitochondria are more susceptible to reacti...
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Principais autores: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864414/ https://ncbi.nlm.nih.gov/pubmed/20176654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq045 |
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