Mitochondrial DNA copy number and lung cancer risk in a prospective cohort study

Mitochondria are eukaryotic organelles responsible for energy production. Mitochondrial DNA (mtDNA) lack introns and protective histones, have limited DNA repair capacity and compensate for damage by increasing the number of mtDNA copies. As a consequence, mitochondria are more susceptible to reacti...

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Autori principali: Hosgood, H.Dean, Liu, Chin-San, Rothman, Nathaniel, Weinstein, Stephanie J., Bonner, Matthew R., Shen, Min, Lim, Unhee, Virtamo, Jarmo, Cheng, Wen-ling, Albanes, Demetrius, Lan, Qing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
Soggetti:
Molecular Epidemiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864414/
https://ncbi.nlm.nih.gov/pubmed/20176654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq045
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