Mitochondrial DNA copy number and lung cancer risk in a prospective cohort study

Mitochondria are eukaryotic organelles responsible for energy production. Mitochondrial DNA (mtDNA) lack introns and protective histones, have limited DNA repair capacity and compensate for damage by increasing the number of mtDNA copies. As a consequence, mitochondria are more susceptible to reacti...

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Autores principales: Hosgood, H.Dean, Liu, Chin-San, Rothman, Nathaniel, Weinstein, Stephanie J., Bonner, Matthew R., Shen, Min, Lim, Unhee, Virtamo, Jarmo, Cheng, Wen-ling, Albanes, Demetrius, Lan, Qing
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
Materias:
Molecular Epidemiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864414/
https://ncbi.nlm.nih.gov/pubmed/20176654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq045
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