Variation in ribosomal DNA copy number is associated with lung cancer risk in a prospective cohort study

Disruption of ribosomal DNA (rDNA) has been linked to a variety of diseases in humans, including carcinogenesis. To evaluate the associations between rDNA copy number (CN) and risk of lung cancer, we measured 5.8S and 18S rDNA CN in the peripheral blood of 229 incident lung cancer cases and 1:1 matc...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Hosgood, H Dean, Hu, Wei, Rothman, Nathaniel, Klugman, Madelyn, Weinstein, Stephanie J, Virtamo, Jarmo R, Albanes, Demetrius, Cawthon, Richard, Lan, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Cancer Biomarkers and Molecular Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736087/
https://ncbi.nlm.nih.gov/pubmed/30859204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgz052
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