Variation in ribosomal DNA copy number is associated with lung cancer risk in a prospective cohort study

Disruption of ribosomal DNA (rDNA) has been linked to a variety of diseases in humans, including carcinogenesis. To evaluate the associations between rDNA copy number (CN) and risk of lung cancer, we measured 5.8S and 18S rDNA CN in the peripheral blood of 229 incident lung cancer cases and 1:1 matc...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Carcinogenesis
Main Authors: Hosgood, H Dean, Hu, Wei, Rothman, Nathaniel, Klugman, Madelyn, Weinstein, Stephanie J, Virtamo, Jarmo R, Albanes, Demetrius, Cawthon, Richard, Lan, Qing
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Cancer Biomarkers and Molecular Epidemiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736087/
https://ncbi.nlm.nih.gov/pubmed/30859204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgz052
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