Cloning, analysis, and expression of murine perforin 1 cDNA, a component of cytolytic T-cell granules with homology to complement component C9.

The nucleotide sequence coding for the cytotoxic T-lymphocyte (CTL) protein perforin 1 (P1) has been determined and the corresponding protein sequence has been derived. Murine CTL cDNA libraries contained in the vector lambda gt11 were screened by using a monospecific antiserum to purified P1. Three...

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Detalhes bibliográficos
Main Authors: Lowrey, D M, Aebischer, T, Olsen, K, Lichtenheld, M, Rupp, F, Hengartner, H, Podack, E R
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC286441/
https://ncbi.nlm.nih.gov/pubmed/2783486
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