Cloning, analysis, and expression of murine perforin 1 cDNA, a component of cytolytic T-cell granules with homology to complement component C9.

The nucleotide sequence coding for the cytotoxic T-lymphocyte (CTL) protein perforin 1 (P1) has been determined and the corresponding protein sequence has been derived. Murine CTL cDNA libraries contained in the vector lambda gt11 were screened by using a monospecific antiserum to purified P1. Three...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Lowrey, D M, Aebischer, T, Olsen, K, Lichtenheld, M, Rupp, F, Hengartner, H, Podack, E R
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1989
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2783486/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.1.247
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