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Cloning, analysis, and expression of murine perforin 1 cDNA, a component of cytolytic T-cell granules with homology to complement component C9.

The nucleotide sequence coding for the cytotoxic T-lymphocyte (CTL) protein perforin 1 (P1) has been determined and the corresponding protein sequence has been derived. Murine CTL cDNA libraries contained in the vector lambda gt11 were screened by using a monospecific antiserum to purified P1. Three...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lowrey, D M, Aebischer, T, Olsen, K, Lichtenheld, M, Rupp, F, Hengartner, H, Podack, E R
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1989
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286441/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2783486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.1.247
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