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Assessing the structural conservation of protein pockets to study functional and allosteric sites: implications for drug discovery
BACKGROUND: With the classical, active-site oriented drug-development approach reaching its limits, protein ligand-binding sites in general and allosteric sites in particular are increasingly attracting the interest of medicinal chemists in the search for new types of targets and strategies to drug...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864279/ https://ncbi.nlm.nih.gov/pubmed/20356358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-10-9 |
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