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High-level erythroid expression of human alpha-globin genes in transgenic mice.
The human alpha 1-globin gene was fused downstream of two erythroid-specific DNase I super-hypersensitive sites that are normally located upstream of the human beta-globin locus. This construct was injected into fertilized mouse eggs, and expression was analyzed in 16-day fetal livers and brains. Al...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1989
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286398/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2911581/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.1.37 |
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