High-level erythroid expression of human alpha-globin genes in transgenic mice.

The human alpha 1-globin gene was fused downstream of two erythroid-specific DNase I super-hypersensitive sites that are normally located upstream of the human beta-globin locus. This construct was injected into fertilized mouse eggs, and expression was analyzed in 16-day fetal livers and brains. Al...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Ryan, T M, Behringer, R R, Townes, T M, Palmiter, R D, Brinster, R L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286398/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2911581/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.1.37
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