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APOBEC3F and APOBEC3G Inhibit HIV-1 DNA Integration by Different Mechanisms

APOBEC3F (A3F) and APBOBEC3G (A3G) both are host restriction factors that can potently inhibit human immunodeficiency virus type 1 (HIV-1) replication. Their antiviral activities are at least partially mediated by cytidine deamination, which causes lethal mutations of the viral genome. We recently s...

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Detalhes bibliográficos
Main Authors: Mbisa, Jean L., Bu, Wei, Pathak, Vinay K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863843/
https://ncbi.nlm.nih.gov/pubmed/20219927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02358-09
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