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APOBEC3F and APOBEC3G Inhibit HIV-1 DNA Integration by Different Mechanisms
APOBEC3F (A3F) and APBOBEC3G (A3G) both are host restriction factors that can potently inhibit human immunodeficiency virus type 1 (HIV-1) replication. Their antiviral activities are at least partially mediated by cytidine deamination, which causes lethal mutations of the viral genome. We recently s...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology (ASM)
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863843/ https://ncbi.nlm.nih.gov/pubmed/20219927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02358-09 |
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