Cytidine Deaminases APOBEC3G and APOBEC3F Interact with Human Immunodeficiency Virus Type 1 Integrase and Inhibit Proviral DNA Formation

APOBEC3G (A3G) is a single-stranded DNA cytidine deaminase that targets retroviral minus-strand DNA and has potent antiviral activity against diverse retroviruses. However, the mechanisms of A3G antiviral functions are incompletely understood. Here we demonstrate that A3G, A3F, and, to a lesser exte...

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Bibliographic Details
Main Authors: Luo, Kun, Wang, Tao, Liu, Bindong, Tian, Chunjuan, Xiao, Zuoxiang, Kappes, John, Yu, Xiao-Fang
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933265/
https://ncbi.nlm.nih.gov/pubmed/17428847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02584-06
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