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Amino-Terminal Region of the Human Immunodeficiency Virus Type 1 Nucleocapsid Is Required for Human APOBEC3G Packaging

APOBEC3G exerts its antiviral activity by targeting to retroviral particles and inducing viral DNA hypermutations in the absence of Vif. However, the mechanism by which APOBEC3G is packaged into virions remains unclear. We now report that viral genomic RNA enhances but is not essential for human APO...

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Detalhes bibliográficos
Main Authors: Luo, Kun, Liu, Bindong, Xiao, Zuoxiang, Yu, Yunkai, Yu, Xianghui, Gorelick, Robert, Yu, Xiao-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC523292/
https://ncbi.nlm.nih.gov/pubmed/15479826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.21.11841-11852.2004
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